Anti-GNAI3抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-GNAI3抗体

Anti-GNAI3抗体

商家询价

产品名称: Anti-GNAI3抗体

英文名称: GNAI3

产品编号: YB--1429R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
  • 联系人 : 陈环环
  • 地址 : 上海市沪闵路6088号龙之梦大厦8楼806室
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 183****2235 点击查看
  • 传真 : 点击查看
  • 邮箱 : shybio@126.com
  • 二维码 : 点击查看

 Anti-GNAI3抗体

产品编号 YB-1429R
英文名称 GNAI3
中文名称 抑制型G蛋白α3抗体
别    名 GAI3; 87U6; FLJ26559; G protein alpha inhibiting 3; G(i) alpha 3; G(i) alpha-3; GNAI3; GNAI3_HUMAN; Guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3; Guanine nucleotide binding protein G(k) alpha subunit; Guanine nucleotide-binding protein G(k) subunit alpha; OTTHUMP00000013368; Gnai3; Guanine nucleotide binding protein (G protein), alpha inhibiting 3; G Alpha i-3.   
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GNAI3:241-354/354 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.

Subunit:
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1. Interacts with RGS12. Interacts (via active GTP- or inactive GDP-bound form) with RGS14.

Subcellular Location:
Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton, centrosome.

Similarity:
Belongs to the G-alpha family. G(i/o/t/z) subfamily.

SWISS:
P08754

Gene ID:
2773

Database links:

Entrez Gene: 2773 Human

Entrez Gene: 14679 Mouse

Entrez Gene: 25643 Rat

Omim: 139370 Human

SwissProt: P08754 Human

SwissProt: Q9DC51 Mouse

SwissProt: P08753 Rat

Unigene: 73799 Human

Unigene: 271703 Mouse

Unigene: 4368 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications