分子量：Calculated MW: 56kDa
Observed MW: 54-59kDa

细胞定位：Cytoplasm, Nucleus

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.