MB67 (T102) Antibody
产品名称: MB67 (T102) Antibody
英文名称: MB67 (T102) Antibody
产品编号: BS2311
产品价格: null
产品产地: USA
品牌商标: Bioworld
更新时间: null
使用范围: WB: 1:500~1:1000 IHC: 1:50~1:200
巴傲得生物科技有限公司
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- 邮编 : 210036
- 所在区域 : 上海
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- 邮箱 : order@biogot.com
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.