FITC标记的锌指蛋白664抗体
产品名称: FITC标记的锌指蛋白664抗体
英文名称: Anti-ZNF664/FITC
产品编号: HZ-16526R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZNF664/FITC Conjugated antibody
FITC标记的锌指蛋白664抗体
英文名称 | Anti-ZNF664/FITC |
中文名称 | FITC标记的锌指蛋白664抗体 |
别 名 | ZFOC1; Zinc finger Organ of Corti 1; Zinc finger protein 176; Zinc finger protein 664; Zinc finger protein from organ of Corti; ZN664_HUMAN; ZNF176; Znf664. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Pig, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 30kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF664 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFOC1, also known as ZNF644 (zinc finger protein 644), ZEP2 (zinc finger motif enhancer-binding protein 2) or BM-005, is a 1,327 amino acid nuclear protein belonging to the Krüeppel C2H2-type zinc-finger protein family. Existing as three alternatively spliced isoforms, ZFOC is involved in transcriptional regulation and contains seven C2H2-type zinc fingers. The gene encoding ZFOC1 maps to human chromosome 12q24.31. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 9 C2H2-type zinc fingers. Database links: Entrez Gene: 144348 Human Entrez Gene: 269704 Mouse SwissProt: Q8N3J9 Human SwissProt: Q4VA44 Mouse Unigene: 524828 Human Unigene: 138617 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
锌指蛋白含有DNA结合结构域,具有多种功能,其中大多数包含某种形式的转录激活或抑制。大多数锌指蛋白包含Krüppel型DNA结合域和KRAB域,它们被认为与KAP1相互作用,从而募集组蛋白修饰蛋白。ZFOC1,又称ZNF644(锌指蛋白644)、ZEP2(锌指基序增强子结合蛋白2)或BM-005,是属于Krüeppel C2H2型锌指蛋白家族的1327个氨基酸核蛋白。ZFOC作为三种可选择的剪接异构体存在,参与转录调控,包含7个C2H2型锌指。编码ZFCU1的基因定位于人类染色体12q24.31。